Cryptococcal Meningitis in Pediatric AIDS
نویسندگان
چکیده
منابع مشابه
Prognostic markers in AIDS-related cryptococcal meningitis.
OBJECTIVE Despite the advent and expanding access to antiretroviral therapy, HIV-associated cryptococcal meningitis (CM) remains a significant cause of mortality and morbidity amongst individuals with this infection in resource-limited settings. METHODS We prospectively studied the clinical, biochemical and mycological parameters of 30 HIV patients diagnosed with cryptococcal meningitis at ou...
متن کاملEarly mycological treatment failure in AIDS-associated cryptococcal meningitis.
Cryptococcal meningitis causes significant morbidity and mortality in persons with AIDS. Of 236 AIDS patients treated with amphotericin B plus flucytosine, 29 (12%) died within 2 weeks and 62 (26%) died before 10 weeks. Just 129 (55%) of 236 patients were alive with negative cerebrospinal fluid (CSF) cultures at 10 weeks. Multivariate analyses identified that titer of cryptococcal antigen in CS...
متن کاملRisk factors in HIV/AIDS patients with cryptococcal meningitis
Cryptococcosis represents a major life-threatening fungal infection in patients with severe HIV infection. Cryptococcal meningoencephalitis is the most common manifestation of cryptococcosis in patients with advanced immunosuppression. Objectives: evaluating risk factors for severe evolution of patients with HIV infection and meningitis. Possible risk factors were analyzed in 33 HIV-infected pa...
متن کاملCryptococcal Meningitis
Virulence probably plays a relatively small role in the outcome of this infection: the crucial factor is the immune status of the host. The most serious infections usually develop, in fact, in patients with defective cell-mediated immunity, for example those with AIDS, organ transplantation, reticuloendothelial malignancy, corticosteroid treatment and sarcoidosis, but not in subjects with neutr...
متن کاملCryptococcal meningitis
© 2004 Blackwell Publishing Ltd the second most common cause of death in HIV infection after tuberculosis (French et al. 2002). Moreover, despite the availability of highly active antiretroviral therapy (HAART), it continues to pose diffi cult management questions in the industrialized world. Questions remain for physicians regarding the optimal combination of antifungal agents, duration of tre...
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ژورنال
عنوان ژورنال: Journal of Tropical Pediatrics
سال: 2003
ISSN: 1465-3664,0142-6338
DOI: 10.1093/tropej/49.2.124